i don't like playing against elise. no clue what she does yet.
She goes squish. Her climb thing isn't that great. Haven't seen any full AP ones so far, but she really doesn't stand out for me so far.
I played her full AP, it was pretty impressive, her W does about 700 damage with 500ish AP.
E to stun, its got a long range, launch W hit Q
R to spider, W for ats boost E if they run and Q to finish it off.
Takes a couple of seconds, but you'll trash anybody who's not super tanky.